Chronic migraine. Chronic migraine without aura, not intractable, without status migrainosus
Conditions
Interventions
Intervention 1: Intervention group: In this group, after administering a single session of botulinum toxin injection for the patients, we will use a zinc supplement at a dose of 50 mg (Suzin 50) manuf
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: The patient’s serum zinc level should be within the normal range before enrollment in the study Patients over 18 years old Diagnosed with chronic migraine No other active diseases Willingness to participate in this study and sign a written informed consent
Exclusion criteria
Exclusion criteria: Severe burns and trauma Active infectious or inflammatory disease Pregnancy and uncontrolled diabetes Consumption of alcohol Moderate to severe liver disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Headache intensity. Timepoint: First visit (before botulinum toxin injection), one month after botulinum toxin injection and receipt of placebo or zinc supplement, six months after botulinum toxin injection and receipt of placebo. Method of measurement: With Migraine Disability Assessment (MIDAS) Score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Hamed Azar
Tabriz University of Medical Sciences
Outcome results
None listed