Skip to content

Effect of cis-atracurium on postoperative delirium

Assessment of the effect of cis-atracurium compared with atracurium on postoperative delirium in colorectal surgeries

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250902067095N1
Enrollment
200
Registered
2025-09-09
Start date
2025-09-23
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colon cancer. Malignant neoplasm of colon

Interventions

Intervention 1: Intervention group 1: 0.2 mg/kg Cis-atracurium for induction of anesthesia and 2 mg cis-atracurium every 45 minutes during maintenance from vials of 2 mg/ml. Intervention 2: Interventi

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who are candidates for elective colorectal surgery Patient age over 40 years Patient consent to participate in the project Patient's non-participation in another clinical trial

Exclusion criteria

Exclusion criteria: Emergency surgeries Trauma patients Patients who are candidates for multiple surgeries (or second or third surgery cases) Patients with a history of anaphylactic reactions, allergies, or asthma

Design outcomes

Primary

MeasureTime frame
Postoperative delirium. Timepoint: Every 12 hours postoperative until day 5. Method of measurement: Intensive Care Delirium Screening Checklist.

Secondary

MeasureTime frame
Postoperative cognitive dysfunction. Timepoint: Fifth day after surgery. Method of measurement: Montreal Cognitive Assessment.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKousha Farhadi

Tehran University of Medical Sciences

koushafarhadi@gmail.com+98 21 2292 0114

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026