Ileus caused by gastric bypass surgery (Roux-en-Y gastric bypass). Paralytic ileus
Conditions
Interventions
Intervention 1: Intervention group: Patients undergoing open Roux-en-Y gastric bypass at Imam Reza Hospital (Mashhad, Iran) will receive oral probiotic capsules starting 24 hours after surgery, 2 caps
labeled 10^18 CFU per capsule
Iran-made). Allocation is randomized with equal assignment and the trial is double-blind (participants, care team, and outcome assessors). All participants receive standard postoperative care equally
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patient presenting for bypass surgery Performing laparotomy surgery on the patient Patient must be between 18 and 60 years old, have informed consent from the patient Complete patient medical record No underlying medical conditions, clinical history, and specific conditions such as diabetes and hypertension, pregnancy, psychiatric problems, disability, or organ defects No nasogastric tube No clinical history or histological confirmation of inflammatory bowel disease
Exclusion criteria
Exclusion criteria: Refusal to continue the study or take medication Failure to take medication at the prescribed time and in the prescribed amount Withdrawal from the study due to transfer to another hospital or sudden personal consent or death of the patient or occurrence of an emergency condition in the patient Leakage of the intestinal anastomosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative ileus, defined as a total score equal to or greater than six on the five-item scoring system of Intake, Feeling nauseated, Emesis (vomiting), physical Examination of the abdomen for distension, and Duration of symptoms, assessed during the postoperative hospitalization after Roux-en-Y gastric bypass surgery. Timepoint: Once daily beginning twenty-four hours after surgery (postoperative day 1) and every twenty-four hours thereafter until hospital discharge. Method of measurement: Bedside clinical assessment using the five-item scoring system of Intake, Feeling nauseated, Emesis (vomiting), physical Examination of the abdomen for distension, and Duration of symptoms; each item is scored from zero to three, the total score ranges from zero to fifteen, and postoperative ileus is defined as a total score equal to or greater than six. Data are recorded on standardized case-report forms and the patient’s medical record. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHashem Fathi
Torbate-Heidaria University of Medical Sciences
Outcome results
None listed