Condition 1: Acute respiratory distress syndrome. Condition 2: Chronic obstructive pulmonary disease with (acute) exacerbation. Condition 3: Asthma. Condition 4: Bronchopneumonia, unspecified organism. Acute respiratory distress syndrome Chronic obstructive pulmonary disease with (acute) exacerbation Asthma Bronchopneumonia, unspecified organism
Conditions
Interventions
Intervention 1: Intervention group: The intervention group, upon admission to the intensive care unit on the first day of hospitalization, will undergo remote ischemic preconditioning (RIPC) twice, wi
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Admission to the intensive care unit due to acute respiratory disorder Relatively stable hemodynamic status (Mean Arterial Pressure = 65 mmHg without the need for vasopressors or at low doses) Filling out an informed consent
Exclusion criteria
Exclusion criteria: Presence of active disease or severe skin damage to the upper limb (open wound, gangrene, infection, recent trauma) History of surgery or severe occlusion of upper extremity arteries Severe heart failure (Left Ventricle Ejection Fraction (LVEF ) < 30% or cardiogenic shock) End-stage Kidney disease Thrombophilia or anticoagulant use with high risk of bleeding Pregnancy Concurrent participation in other clinical studies Length of hospitalization less than 7 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Respiratory Index. Timepoint: First, third, and seventh day of hospitalization. Method of measurement: Calculation via formula based on patient laboratory results.;Ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen. Timepoint: First, third, and seventh day of hospitalization. Method of measurement: Calculation based on patient laboratory results. | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of stay in the intensive care unit. Timepoint: At discharge. Method of measurement: Based on the patient's records.;Intubation. Timepoint: At discharge. Method of measurement: Based on the patient's record indicating the need for intubation.;Clinical outcome. Timepoint: At discharge. Method of measurement: Based on the patient's record of recovery or death. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohsen Farrokhpour
Iran University of Medical Sciences
Outcome results
None listed