Skip to content

Investigating the effect of rTMS on improving cognitive and behavioral performance in patients with Parkinson's disease

Investigating the effect of rTMS on improving cognitive and behavioral performance in patients with Parkinson's disease

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250901067072N1
Enrollment
92
Registered
2025-11-14
Start date
2025-12-06
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's. Parkinson's disease

Interventions

Intervention 1: Intervention group: Undergo rTMS treatment. The treatment will be performed using a high-frequency (10 Hz) rTMS device to stimulate the dorsolateral prefrontal cortex (DLPFC). The numb

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients between 40 and 80 years of age. Patients should have mild to moderate cognitive impairment, such that memory, attention, and executive function impairments can be identified.

Exclusion criteria

Exclusion criteria: Patients who change their medication or receive new medications for Parkinson's disease or psychiatric disorders during the study period. Patients whose symptoms worsen significantly or who experience severe side effects from treatment during the study.

Design outcomes

Primary

MeasureTime frame
Cognitive function. Timepoint: To assess cognitive function, the MMSE (Mini-Mental State Examination) and MoCA (Montreal Cognitive Assessment) scales will be used. Executive dysfunction, memory, attention, and language will be assessed using validated tests such as the Stroop Test and the Trail Making Test. Method of measurement: To assess cognitive function, the MMSE (Mini-Mental State Examination) and MoCA (Montreal Cognitive Assessment) scales will be used. Executive dysfunction, memory, attention, and language will be assessed using validated tests such as the Stroop Test and the Trail Making Test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArash Amini

Islamic Azad University

ar.amini200@gmail.com+98 21 2660 2642

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026