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Safety of Polypropylene mesh in hernia treatment

Safety evaluation of synthesized Polypropylene mesh in the repair of abdominal organ protrusions: Phase 1 clinical trial

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250827067021N1
Enrollment
7
Registered
2025-09-17
Start date
2025-10-02
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal Hernia. Unspecified abdominal hernia without obstruction or gangrene

Interventions

Intervention group: Seven patients with abdominal hernia who require herniorrhaphy surgery are included in this group. Polypropylene meshes measuring 6 cm by 11 cm are implanted at the hernia site and

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: All patients requiring abdominal hernia repair with surgical mesh.

Exclusion criteria

Exclusion criteria: People with underlying disease as anemia, diabetes, cardiovascular diseases, malignancy and immunodeficiency. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
Local complications. Timepoint: 7, 14 and 21 days after surgery. Method of measurement: Examination and observing erythema or purulent discharge.;Systemic complications. Timepoint: 7, 14 and 21 days after surgery. Method of measurement: Measurement of body temperature, pulse rate per minute, respiratory rate per minute and blood pressure.

Secondary

MeasureTime frame
Recurrence of hernia. Timepoint: 7, 14 and 21 days after surgery. Method of measurement: Examination and observation.;Wound healing rate. Timepoint: 7, 14 and 21 days after surgery. Method of measurement: Observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPirooz Samidoost

Rasht University of Medical Sciences

razi.hospital@yahoo.com+98 13 3354 1001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026