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Investigating the effect of changing serum concentration on the treatment of hypernatremia

Evaluation of the effectiveness of IV fluid with sodium of 100 mEq/L compared to 77 mEq/L in the treatment of hypernatremia caused by gastroenteritis: a clinical trial study

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250825066983N1
Enrollment
186
Registered
2025-11-15
Start date
2026-01-05
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroenteritis with hypernatremia. Hyperosmolality and hypernatremia

Interventions

Intervention 1: Intervention group Group A: Recipient of intravenous fluid therapy of 100 milliequivalents per liter of sodium.The rate of sodium correction will be carried out in accordance with stan

Sponsors

Ghoum University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Months to 18 Years

Inclusion criteria

Inclusion criteria: Clinical and laboratory diagnosis of gastroenteritis Serum sodium level greater than 160 mEq/L Age between 1 month and 18 years

Exclusion criteria

Exclusion criteria: Patients with chronic renal or metabolic diseases Patients in severe hemodynamic shock Patients with pre-existing cerebral or neurological disorders Parental unwillingness to participate in the study Before randomization

Design outcomes

Primary

MeasureTime frame
Electrolyte disturbances, difference between sodium in hypernatremic patients and sodium in intravenous fluid therapy. Timepoint: Before treatment, at intervals of every 6 hours. Method of measurement: Medical diagnostic test.

Secondary

MeasureTime frame
Correction of blood sodium. Timepoint: At intervals of every 6 hours to 24 hours. Method of measurement: Medical diagnostic test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyyed Amir Vaezzadeh

Ghoum University of Medical Sciences

Vaezzadeha951@gmail.com+98 25 3162 5224

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026