The Effect of Integrating Pain Neuroscience Education(PNE) with Conventional Physiotherapy in the treatment of Acute Low Back Pain

The Effect of Integrating Pain Neuroscience Education(PNE) with Conventional Physiotherapy on Pain and Functional Disability in Patients with Acute Low Back Pain

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250824066976N1

Enrollment

Registered

2025-10-04

Start date

2025-10-23

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Low Back Pain. Low back pain

Interventions

Intervention 1: Intervention group: Intervention group: Routine physiotherapy treatment for acute low back pain + pain neuroscience education. Intervention 2: Control group: Routine physiotherapy trea

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Persistent back pain for less than 6 weeks with or without leg pain Willingness to participate in the study

Exclusion criteria

Exclusion criteria: Complaints of back pain with or without leg pain for more than 6 weeks History of back surgery within the past three years Inability to read or understand Persian Diagnosed cognitive disorders Diagnosed rheumatological, neurological, cardiac, metabolic, and respiratory diseases Having fibromyalgia, chronic fatigue syndrome, loss of skin sensation, inflammation or swelling in the skin of the lower back area Presence or occurrence of a red flag associated with back pain. Red flags associated with back pain include tumors, infections, fractures, and significant nerve root compression such as cauda equina syndrome. History of participating in neuroscience pain training sessions

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Before the first session - End of the eighth session. Method of measurement: Visual Analogue Scale.;Functional Disability. Timepoint: Before the first session, end of the eighth session. Method of measurement: Oswestry Questionnaire.	—

Secondary

Measure	Time frame
Pain Catastrophizing. Timepoint: Before the first session, end of the eighth session. Method of measurement: Pain Catastrophizing Scale.;Kinesiophobia. Timepoint: Before the first session, end of the eighth session. Method of measurement: Tampa Scale of Kinesiophobia.;Fear-Avoidance Beliefs. Timepoint: Before the first session, end of the eighth session. Method of measurement: Fear-Avoidance Beliefs Questionnaire.	—

Measure

Time frame

Pain Catastrophizing. Timepoint: Before the first session, end of the eighth session. Method of measurement: Pain Catastrophizing Scale.;Kinesiophobia. Timepoint: Before the first session, end of the eighth session. Method of measurement: Tampa Scale of Kinesiophobia.;Fear-Avoidance Beliefs. Timepoint: Before the first session, end of the eighth session. Method of measurement: Fear-Avoidance Beliefs Questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiloofar Rezaei

Iran University of Medical Sciences

niloofarrezaei.79@gmail.com+98 21 2225 6434

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026