Chronic non-specific low back pain.
Conditions
Interventions
Intervention 1: Intervention group: Participants in the intervention group will undergo an eight-week researcher-designed rehabilitation exercise protocol, consisting of 24 supervised sessions (three
resistance and core stability exercises by increasing repetitions and adopting more advanced variations
and stretching exercises by gradually increasing duration and range of motion.The protocol also incorporates safety adjustments: if participants experience pain or symptom aggravation, they will be in
Sponsors
Kharazmi University
Eligibility
Sex/Gender
Male
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: Males aged 20 to 55 years At least three months history of chronic low back pain with or without referred pain to lower limbs No use of strong anti-inflammatory medications Pain intensity between 3 and 7 on the VAS scale during physical activity No participation in similar exercise therapy during the past three months
Exclusion criteria
Exclusion criteria: Absence in more than three consecutive sessions or five non-consecutive sessions Severe spinal deformities such as scoliosis with Cobb angle greater than 10 degrees, spondylolisthesis, or spinal canal stenosis Severe neurological deficits including significant motor weakness or signs of nerve root compression Recent lumbar or abdominal surgery affecting low back pain status Severe psychiatric disorders interfering with participation in the study Presence of inflammatory or autoimmune diseases such as rheumatoid arthritis, lupus, or ankylosing spondylitis Musculoskeletal problems such as severe knee or hip osteoarthritis affecting study outcomes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity of patients. Timepoint: At baseline (pre-test) and 72 hours after the last training session (post-test). Method of measurement: Using the Visual Analogue Scale (a ten-centimeter horizontal line). | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum level of Interleukin-6. Timepoint: Two days before the start of the intervention and seventy-two hours after the end of the intervention. Method of measurement: Serum interleukin-6 levels will be measured using a commercial ELISA kit.;Serum level of Interleukin 10. Timepoint: Two days before the start of the intervention and seventy-two hours after the end of the intervention. Method of measurement: Serum interleukin-10 levels will be measured using a commercial ELISA kit.;Serum level of Interleukin 13. Timepoint: Two days before the start of the intervention and seventy-two hours after the end of the intervention. Method of measurement: Serum interleukin-13 levels will be measured using a commercial ELISA kit.;Serum level of Tumor Necrosis Factor Alpha. Timepoint: Two days before the start of the intervention and seventy-two hours after the end of the intervention. Method of measurement: Serum Tumor Necrosis Factor Alpha levels will be measured using a commercial ELISA kit.;Serum level of Interleukin 8. Timepoint: Two days before the start of the intervention and seventy-two hours after the end of the intervention. Method of measurement: Serum interleukin-8 levels will be measured using a commercial ELISA kit.;Serum level of Interleukin 1 beta. Timepoint: Two days before the start of the intervention and seventy-two hours after the end of the intervention. Method of measurement: Serum Interleukin-1 beta levels will be measured using a commercial ELISA kit.;????? ??????? ?? ???? ???????? ???????. Timepoint: Two days before the start of the intervention and seventy-two hours after the end of the intervention. Method of measurement: Functional disability will be measured using the Oswestry Disability Index questionnaire.;???? ????? ?????. Timepoint: Two days before the start of the intervention and seventy-two hours after the end of the intervention. Method of measurement: Quality of life will be measured using a standard Quality of Life questionnaire.;??? ????? | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammadjavad Ahmadi
Kharazmi University
Outcome results
None listed