Evaluating the effect of subcutaneous tranexamic acid injection on scar formation

Evaluating the effect of subcutaneous tranexamic acid injection versus placebo on scar formation in patients undergoing abdominoplasty and bilateral mammoplasty

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250820066933N1

Enrollment

Registered

2025-10-24

Start date

2025-11-09

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Scar feature in abdominoplasty and bilateral mammoplasty.

Interventions

Intervention 1: Intervention group: women over 18 years old who need abdominoplasty and bilateral mammoplasty. After finishing surgery, 100 mg/ml tranexamic acid from Capian company will be injected i

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Women over 18 years old Need bilateral abdominoplasty or Mammoplasty

Exclusion criteria

Exclusion criteria: Surgical history of abdominoplasty or mammoplasty Unilateral abdominoplasty or mammoplasty History of any thromboembolic disease Pregnancy Any severe diseases Women who use antiplatelet drugs or anticoagulant drugs

Design outcomes

Primary

Measure	Time frame
Wound healing. Timepoint: Six months after injection. Method of measurement: Vancouver scoring system.;Vascularity. Timepoint: Six months after injection. Method of measurement: Vancouver scoring system.;Pigmentation. Timepoint: Six months after injection. Method of measurement: Vancouver scoring system.;Pliability. Timepoint: Six months after injection. Method of measurement: Vancouver scoring system.;Wound height. Timepoint: Six months after injection. Method of measurement: Vancouver scoring system.	—

Measure

Time frame

Wound healing. Timepoint: Six months after injection. Method of measurement: Vancouver scoring system.;Vascularity. Timepoint: Six months after injection. Method of measurement: Vancouver scoring system.;Pigmentation. Timepoint: Six months after injection. Method of measurement: Vancouver scoring system.;Pliability. Timepoint: Six months after injection. Method of measurement: Vancouver scoring system.;Wound height. Timepoint: Six months after injection. Method of measurement: Vancouver scoring system.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirmorteza Rezazadeh

Tehran University of Medical Sciences

amirmortezarezazadeh1367@gmail.com+98 21 6119 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026