Studying the effect of preoperative melatonin on postoperative pain in patients undergoing abdominal surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250816066877N1

Enrollment

Registered

2025-09-09

Start date

2025-10-23

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after surgery. Other chronic pain

Interventions

Intervention 1: Intervention group: Melatonin tablets 3 mg, administered once, used sublingually by the patient, manufactured by Galenus Pharmaceuticals. Intervention 2: Control group: A sublingual ta

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Elective surgery ASA1,2

Exclusion criteria

Exclusion criteria: Unusual intraoperative bleeding Operative duration >4 hours

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 1, 6 and 24 hours after surgery. Method of measurement: Based on the VAS scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Javad Waziri

Islamic Azad University

mohamadjv.999@gmail.com+98 21 2660 2642

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026