Functional Constipation. Constipation
Conditions
Interventions
Intervention 1: Control group: Participants will receive conventional pelvic floor physiotherapy, which includes biofeedback using a rectal electrode for retraining and strengthening the anorectal mus
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Female participants aged 20 to 60 years who meet the Rome III criteria for chronic functional constipation
Exclusion criteria
Exclusion criteria: Currently receiving any other treatment for chronic functional constipation Previous treatment for chronic functional constipation within the past month Presence of any organic disorder known to cause constipation Diagnosis of neurological disorders (multiple sclerosis, Parkinson’s disease, or spinal cord injury) Presence of diabetic neuropathy Presence of congenital anomalies of the anorectal region Presence of anatomical disorders requiring surgical intervention (mucosal prolapse, rectocele, cystocele) as determined by a specialist Suffering from major depression (Beck Depression Inventory score > 30) Use of medications known to induce constipation (e.g., antidepressants, antihistamines, antiepileptic drugs) Previous anorectal surgery Current pregnancy or intention to become pregnant Prescence of periodontal disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Salivary acetylcholine esterase. Timepoint: Baseline (prior to intervention), midpoint, and end of study. Method of measurement: Collection of unstimulated saliva sample and analysis using an acetylcholinesterase assay kit.;Hear Rate Variability. Timepoint: Baseline (prior to intervention), midpoint, and end of study. Method of measurement: Electrocardiography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical symptoms of chronic functional constipation. Timepoint: Baseline (prior to intervention), midpoint, and end of study. Method of measurement: Wexner constipation scoring system questionnaire.;Quality of life. Timepoint: Baseline (prior to intervention), midpoint, and end of study. Method of measurement: Patient Assessment of Constipation-Quality of Life questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactParnian Mirbehresi
Iran University of Medical Sciences
Outcome results
None listed