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Comparison of the effect of coconut oil and pomegranate peel extract mouthwash on plaque-induced gingivitis with chlorhexidine mouthwash

Comparison of the effect of coconut oil and pomegranate peel extract mouthwash on plaque-induced gingivitis with chlorhexidine mouthwash

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250811066829N1
Enrollment
40
Registered
2025-10-06
Start date
2025-10-12
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with gingivitis. Chronic gingivitis, plaque induced

Interventions

Intervention 1: Intervention group :The study group of 20 people will use 10ml of mouthwash containing coconut oil twice a day after waking up and before going to bed for 2 minutes. Intervention 2: Co

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The age range of people is between 18 and 65 years old. Have clinical signs of gingivitis. Have plaque and calculus on tooth surfaces

Exclusion criteria

Exclusion criteria: People with any systemic disease. Pregnant and breastfeeding mothers. People who used mouthwash. People who have had chemotherapy or are being treated with antibiotics. Patients with poor motivation and/or poor cooperation. Patients treated with calcium antagonists, cyclosporine, and phenytoin. Patients who are allergic to coconut.

Design outcomes

Primary

MeasureTime frame
Plaque Index: This refers to the presence or absence of plaque on the 6 surfaces of the teeth, which is measured on all teeth present in the patient's mouth. Timepoint: 14 days after using mouthwash. Method of measurement: The plaque index (DPI) is calculated using the O'Leary index (this index is useful for assessing the plaque control performance of patients and is relatively easy, reproducible and inexpensive to determine). For this purpose, the patient's mouth is first rinsed with plain water and the surfaces of his teeth are stained using a dye that is revealed to detect dental plaque. In the next step, the discoloration of the different surfaces of each tooth is examined. For this purpose, each stained surface will be examined for the accumulation of plaque-revealing tablets at the tooth-gingival junction and the stained areas will be recorded with a red mark on the form. Finally, the number of discolored surfaces is divided by the number of teeth multiplied by six (or the total number of stained surfaces) and expressed as a percentage.;Gingival index :The gingival index (GI) is defined as a tool used to assess the severity of gingival inflammation based on the thickness and accumulation of plaque and debris, which helps evaluate patient adherence to oral hygiene practices. Timepoint: 14 days after using mouthwash. Method of measurement: The gingival index is recorded by the examiner using a Williams probe. The Löe & Silness method is used to assess the gingival index. The gingiva of each tooth is divided into four sections: mesiobuccal, distobuccal, midbuccal, and midlingual. Each section is scored from 0 to 3. If the gingiva appears normal and is not bleeding, a score of 0 is assigned; if there is little inflammation and no bleeding on probing, a score of 1; if there is moderate inflammation and bleeding on probing, a score of 2; and if there is severe inflammation and spontaneous bleeding, a score of 3. To obtain the gingival index of each tooth, the averag

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarshad Javadzadeh

Tabriz University of Medical Sciences

Fa.javadzadeh@gmail.com+98 41 3336 3298

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026