Transient Tachypnea of newborn. Transient tachypnea of newborn
Conditions
Interventions
Intervention 1: intervention group: they will receive a single dose of inhaled salbutamol (Ventolin, manufactured by Cipla, India) at a dose of 0.15 milligram equivalent to 0.15 milliliter per kilogra
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 28 Days
Inclusion criteria
Inclusion criteria: Neonates with gestational age at term, near-term, or post-term Presence of clinical manifestations and history suggestive of TTN At least one radiologic criterion of TTN, including:Pulmonary hyperinflationBilateral perihilar vascular prominenceFluid in the transverse fissureOr similar findings
Exclusion criteria
Exclusion criteria: History of meconium aspiration Respiratory distress syndrome (RDS) Congenital pneumonia Polycythemia Hypoglycemia Proven early-onset sepsis Congenital heart disease Tachycardia exceeding 180 beats per minute Cardiac arrhythmia Congenital anomalies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Respiratory distress score. Timepoint: Before treatment and after treatment at intervals of 30 minutes, one hour, and four hours. Method of measurement: This system is a clinical tool for assessing the severity of respiratory distress in neonates. It evaluates five main indicators: grunting, nasal flaring, xiphoid retraction, lower chest retraction, and upper chest retraction.Method of measurement: Each indicator is evaluated by direct clinical observation of a trained physician or nurse, including the presence or absence of sounds such as grunting with a stethoscope, assessment of nasal wing movements, and observation and palpation of chest wall movements in different regions during inspiration and expiration.Scoring system: For each of the five indicators, the severity of findings is scored from 0 to 2.Score 0: No sign or normal condition (for example, no grunting, no retraction).Score 1: Mild or minimal finding (for example, grunting audible with stethoscope, slight retraction or nasal flaring).Score 2: Clear or severe finding (for example, grunting audible without stethoscope, marked nasal flaring, severe chest retraction with see-saw breathing).Final interpretation: The total score ranges from 0 to 10. Lower scores indicate mild or absent respiratory distress, while higher scores represent more severe distress requiring further intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of Hospital Stay. Timepoint: At admission and at discharge. Method of measurement: Based on the patient’s medical records.;Respiratory Rate. Timepoint: Before starting treatment, 30 minutes, one hour, and four hours after. Method of measurement: Counting the respiratory rate for one minute based on abdominal and chest movements of the neonate.;Heart rate. Timepoint: Before starting treatment, 30 minutes, one hour, and four hours after. Method of measurement: Based on pulse oximetry information.;Oxygen saturation. Timepoint: Before starting treatment, 30 minutes, one hour, and four hours after. Method of measurement: Based on pulse oximetry information. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Mahdi Foruhari
Kashan University of Medical Sciences
Outcome results
None listed