Effects of Endovascular Angiography and Sclerotherapy on Quality of Life and Symptom Severity in Patients with Venous Insufficiency

Comparison of the Effects of Endovascular Angiography and Sclerotherapy on Quality of Life and Symptom Severity in Patients with Venous Insufficiency

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250804066752N1

Enrollment

Registered

2025-08-22

Start date

2025-09-23

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Venous Insufficiency. Venous insufficiency (chronic) (peripheral)

Interventions

Intervention 1: Intervention Group 1 (endovascular angiography): In this study, patients with chronic venous insufficiency who refer to treatment centers for treatment are randomly assigned to the end

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Adult patients (aged 18–75 years) with chronic venous insufficiency of severity grade I to III (according to the CEAP classification), for whom both treatment methods are deemed appropriate and applicable by the treating physician. No similar treatments in the past 6 months Ability to complete quality of life questionnaires Willingness to participate in the study and sign an informed consent form

Exclusion criteria

Exclusion criteria: Lack of follow-up after treatment. Inability to complete the questionnaires related to quality of life and symptom severity. Occurrence of serious treatment-related adverse events.

Design outcomes

Primary

Measure	Time frame
Quality of life and symptom severity based on the VEINES-QOL/SYM questionnaire. Timepoint: 1 month. Method of measurement: VEINES-QOL/SYM questionnaire- The VEINES-QOL/SYM questionnaire is a valid and reliable tool for assessing quality of life and symptom severity in patients with chronic venous insufficiency. The questionnaire consists of two main parts:Quality of life section (VEINES-QOL): This section assesses the impact of venous insufficiency on various aspects of the patient's life (including daily activities, sleep, physical activity, emotional concerns, etc.).Symptom severity section (VEINES-SYM): This section includes questions that assess the severity of symptoms associated with venous insufficiency, such as pain, swelling, heaviness in the legs, and skin problems.The questionnaire consists of 14 questions to assess quality of life and 7 questions to assess symptom severity. Responses are recorded on a 5-point Likert scale (from 1 to 5).	—

Measure

Time frame

Quality of life and symptom severity based on the VEINES-QOL/SYM questionnaire. Timepoint: 1 month. Method of measurement: VEINES-QOL/SYM questionnaire- The VEINES-QOL/SYM questionnaire is a valid and reliable tool for assessing quality of life and symptom severity in patients with chronic venous insufficiency. The questionnaire consists of two main parts:Quality of life section (VEINES-QOL): This section assesses the impact of venous insufficiency on various aspects of the patient's life (including daily activities, sleep, physical activity, emotional concerns, etc.).Symptom severity section (VEINES-SYM): This section includes questions that assess the severity of symptoms associated with venous insufficiency, such as pain, swelling, heaviness in the legs, and skin problems.The questionnaire consists of 14 questions to assess quality of life and 7 questions to assess symptom severity. Responses are recorded on a 5-point Likert scale (from 1 to 5).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHaleh Jafari

Tehran University of Medical Sciences

halejafari67@gmail.com+98 21 6692 7171

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026