The Effect of Ora-Aid Dressing on Inflammation, Pain, and Wound Healing.

The Effect of Ora-Aid Dressing on Inflammation, Pain, and Wound Healing at the Free Gingival Graft Donor Site: A Randomized Clinical Trial.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250804066750N1

Enrollment

Registered

2025-08-31

Start date

2025-09-22

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Palatal donor site wound after free gingival graft surgery.

Interventions

Intervention 1: Intervention group (Ora-Aid): After surgery, a ready-to-use Ora-Aid dressing will be applied directly to the palatal donor site according to the manufacturer's instructions. The dressi

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients eligible for FGG surgical treatment Systemically healthy patients Age between 18 and 60 years No medications affecting the inflammatory response or wound healing (such as corticosteroids, Non-Steroidal Anti-Inflammatory Drug: NSAIDs, or immunosuppressive drugs within the last 1 month) No history of periodontal surgery in the donor area within the last 6 months Written informed consent to participate in the study Patients with no history of smoking Patients with no systemic conditions affecting wound healing

Exclusion criteria

Exclusion criteria: Pregnant patients or lactating mothers Patient non-cooperation in follow-ups or failure to attend 14-day visit Change in patient's systemic or drug conditions that may affect study results Patients with uncontrolled systemic conditions Patients with bleeding disorders

Design outcomes

Primary

Measure	Time frame
Pain intensity. Timepoint: Immediately after surgery and 14 days after surgery. Method of measurement: Visual Analogue Scale.;Wound Healing. Timepoint: 14 days after surgery. Method of measurement: Wound Healing Index.	—

Secondary

Measure	Time frame
Inflammatory biomarker IL-1ß in saliva. Timepoint: Before surgery and 14 days after surgery. Method of measurement: enzyme-linked immunosorbent assay (ELISA).;Anti-inflammatory biomarker IL-10 in saliva. Timepoint: Before surgery and 14 days after surgery. Method of measurement: enzyme-linked immunosorbent assay (ELISA).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamidreza Eghbalikhosro

Shahid Beheshti University of Medical Sciences

hamidrezaeghbali19@gmail.com+98 21 2217 5351

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026