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Investigating the effect of probiotics on children's quality of life and respiratory quality

Studying the effect of probiotic consumption on the quality of life and respiratory quality of children with primary ciliary motility disorder (PCD)

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250802066730N1
Enrollment
19
Registered
2025-09-29
Start date
2025-12-21
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Ciliary Dyskinesia. Other diseases of bronchus, not elsewhere classified

Interventions

Intervention group: Initially, children with primary ciliary movement disorder will be given a placebo for four months, then the intervention in the group will be carried out in such a way that one c

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 18 Years

Inclusion criteria

Inclusion criteria: The child must be diagnosed with primary ciliary motility disorder. The child's parents must consent to participate in the study. - Has not previously been hospitalized in a hospital or other medical center for treatment of the current illness.

Exclusion criteria

Exclusion criteria: The child has an underlying condition that affects the indicators of quality of life and respiratory status. The child is uncooperative for performing spirometry.

Design outcomes

Primary

MeasureTime frame
Quality of life. Timepoint: Before the intervention, 4 months after starting the placebo, 4 months after the intervention and giving probiotics. Method of measurement: Children's Quality of Life Questionnaire by Vani et al.;Breathing quality. Timepoint: Before the intervention, 4 months after starting the placebo, 4 months after the intervention and giving probiotics. Method of measurement: Spirometry and respiratory status indices in children Lucas et al. (2019).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZoha Oghabian

Tehran University of Medical Sciences

zoha.oghabian94@gmail.com+98 21 8889 8532

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026