Comparison Of Hypofractionated And Conventional Radiotherapy In Advanced Breast Cancer

Comparison Of Local Control And Complications Of Hypofractionated Radiotherapy With Conventional In Patients With Advanced Breast Cancer

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250728066668N1

Enrollment

200

Registered

2025-08-01

Start date

2025-08-06

Completion date

Unknown

Last updated

2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer. Malignant neoplasm of breast

Interventions

Intervention 1: Intervention Group:Patients with advanced breast cancer undergo hypofractionated radiotherapy treatment for three weeks. During treatment, they are monitored weekly for complications b

Eligibility

Sex/Gender

Female

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: All Patients With Advanced Breast Cancer And Confirmed Histologic Diagnosis With Negative Surgical Margin

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Acute Complication of Hypofraction And Conventional. Timepoint: Patients will be seen weekly during radiotherapy and once a month afterwards for treatment complications. Method of measurement: A checklist designed based on CTCAE v5.0 (radiotherapy-induced dermatitis), RTOG (subcutaneous toxicity) and SOMA/LENT (telangiectasia, hand edema, pain in the radiotherapy area) will be completed to review the complications of interest.	—

Measure

Time frame

Acute Complication of Hypofraction And Conventional. Timepoint: Patients will be seen weekly during radiotherapy and once a month afterwards for treatment complications. Method of measurement: A checklist designed based on CTCAE v5.0 (radiotherapy-induced dermatitis), RTOG (subcutaneous toxicity) and SOMA/LENT (telangiectasia, hand edema, pain in the radiotherapy area) will be completed to review the complications of interest.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNajme Radmard

Babol University of Medical Sciences

Radmardnajme1@gmail.com+98 11 3219 9592

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026