Chronic kidney disease in hemodialysis patients.
Conditions
Interventions
Intervention 1: Intervention group:In the intervention group, oral melatonin will be administered at a dose of three milligrams per day, taken one hour before bedtime, for a duration of twelve weeks.
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Participants must be within a specific age range, typically 18 years or older. Diagnosis of Chronic Kidney Disease:Participants must have chronic kidney failure and must have been undergoing hemodialysis for at least three months. Willingness to Participate:Participants must provide informed consent indicating their willingness to participate in the study.
Exclusion criteria
Exclusion criteria: Withdrawal of Consent:If the patient decides to discontinue participation in the study at any time. .New Medical Conditions:Development of any new illness or medical condition requiring hospitalization or surgery. .Irregular Attendance:Inability of the patient to attend dialysis sessions regularly. .Change in Treatment Status:If the patient undergoes other treatments such as kidney transplantation or peritoneal dialysis during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum ferritin. Timepoint: Patients’ ferritin, and hematocrit levels will be measured before the intervention. After 12 weeks of melatonin supplementation, ferritin, levels will be reassessed. Method of measurement: Using standard measurement kits. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemoglobin. Timepoint: At baseline (before the intervention) and after 12 weeks. Method of measurement: According to the standard dialysis protocols in Iran, a routine blood sample is taken from all dialysis patients every three months, and the hemoglobin level is measured using standard specific kits by the laboratory of Imam Hospital.;Albomin. Timepoint: At baseline (before the intervention) and after 12 weeks. Method of measurement: According to the standard dialysis protocols in Iran, a routine blood sample is taken from all dialysis patients every three months, and the serum albumin level is measured using standard specific kits by the laboratory of Imam Hospital. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShahla Ahmadi Halili
Ahvaz University of Medical Sciences
Outcome results
None listed