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Evaluating the Efficacy of Oxytocin in Reducing Intraoperative Blood Loss During Abdominal Myomectomy

Evaluating the Efficacy of Oxytocin in Reducing Intraoperative Blood Loss During Abdominal Myomectomy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250726066636N1
Enrollment
94
Registered
2025-08-11
Start date
2025-09-23
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal myomectomy surgery. Leiomyoma of uterus

Interventions

Intervention 1: Intervention group: Intravenous infusion of oxytocin at a dose of 30 international units (IU) diluted in 500 ml of normal saline. Intervention 2: Control group: Intravenous infusion 50

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Women aged 18 to 45 Diagnosis of symptomatic intramural uterine fibroids with a size greater than 5 cm and 1-3 in number Uterine size 14-16 weeks

Exclusion criteria

Exclusion criteria: Patients with known bleeding disorders People who are on anticoagulant therapy Patients with liver disease, cardiomyopathy, congestive heart failure, ischemic heart disease, hypertension, dyslipidemia, diabetes, recent vascular thrombosis, gynecological malignancy Previous treatment with Gonadotropin-releasing hormone Hemoglobin below 10 Lactating women Patients with a history of allergic reactions to oxytocin or other contraindications to its use Patients with a BMI greater than 35 kg/m2 Patients with multiple large myomas, which can significantly alter the standard abdominal myomectomy procedure.

Design outcomes

Primary

MeasureTime frame
Blood loss. Timepoint: Before and after surgery. Method of measurement: By measuring the number of gas and bottle suction during surgery and measuring hemoglobin levels using standard laboratory methods before and after surgery.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFereshteh Odar

Qazvin University of Medical Sciences

odarfereshteh@gmail.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026