Postoperative Nausea and Vomiting Following Strabismus Surgery.
Conditions
Interventions
Intervention 1: Intervention group: Patients in Group A will receive oral aprepitant at a dose of 1 mg/kg (maximum dose: 40 mg) one hour prior to anesthesia induction. Intervention 2: Intervention gro
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Has ASA level I or II. Informed consent to participate in the study
Exclusion criteria
Exclusion criteria: Pregnant or breastfeeding mothers Patients treated with antiemetic drugs (such as ondansetron, granisetron, metoclopramide, domperidone, chlorpromazine, etc.), steroid drugs, or current or past use of any drug or opioid that causes vomiting. History of vomiting due to any other organic cause Sensitivity to any of the study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence and severity of postoperative nausea and vomiting (PONV) will be recorded. PONV severity will be assessed using the Visual Analogue Scale (VAS), ranging from 0 (no nausea) to 10 (the most severe imaginable nausea). The number of vomiting episodes will also be documented separately. Timepoint: Data will be recorded at 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: ?he severity of nausea will be assessed using the Visual Analogue Scale (VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Patients' DBP, SBP, HR, and SpO2 will be recorded. Timepoint: At 2, 4, 6, 12, and 24 hours postoperatively. Method of measurement: Dedicated hemodynamic monitoring for each patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlireza Hoghoghi
Esfahan University of Medical Sciences
Outcome results
None listed