Fatty Liver. Fatty (change of) liver, not elsewhere classified
Conditions
Interventions
Intervention 1: Intervention group: They will consume 10 grams of inulin daily, prepared by Nazhvan Giah Company, one hour after each meal, along with a glass of water, for 8 weeks. Intervention 2: Co
Sponsors
Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: Liver patients who have not received supplements in the last 2 months. Patients with grade 2 and higher alcoholic fatty liver disease as diagnosed by a gastroenterologist and liver specialist. Age range 30-70 years Consent to participate in the study
Exclusion criteria
Exclusion criteria: Pregnancy and breastfeeding Having a variety of chronic diseases including cardiovascular diseases, diabetes, lung diseases, kidney diseases and cancer People with sensitivity to inulin supplements Taking any type of probiotic, prebiotic and synbiotic supplement Taking drugs that affect the liver and anti-inflammatory Taking antibiotics for a long time in the past 3 months Drinking alcohol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood sugar. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Laboratory kit.;Total Cholesterol. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Laboratory kit.;Triglycerides. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Laboratory kit.;Low-density lipoprotein. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Laboratory kit.;High-density lipoprotein. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Laboratory kit.;Alanine aminotransferase. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Laboratory kit.;Aspartate transaminase. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Laboratory kit.;Weight. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Digital scale.;Waist circumference. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Tape measure.;Fat mass. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Body analyzer.;Fat free mass. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Body analyzer.;Liver fibrosis index. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Formula.;Body mass index. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Formula. | — |
Secondary
| Measure | Time frame |
|---|---|
| Energy intake. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Food Record Questionnaire and Nutritionist IV Software.;Macronutrient intake. Timepoint: At the beginning of the study and 8 weeks after starting inulin or placebo. Method of measurement: Food Record Questionnaire and Nutritionist IV Software. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamed Jafari-Vayghan
Arak University of Medical Sciences
Outcome results
None listed