Carpal Tunnel Syndrome. Carpal tunnel syndrome, unspecified upper limb
Conditions
Interventions
Intervention 1: Conventional Carpal Tunnel Release (CTR): Patients assigned to this group will undergo standard open carpal tunnel release surgery. Under local anesthesia and sterile conditions, a lon
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Definitive diagnosis of Carpal Tunnel Syndrome (CTS) based on clinical and electrodiagnostic criteria.Definition of Carpal Tunnel Syndrome (CTS):CTS is a compressive neuropathy caused by compression of the median nerve within the carpal tunnel of the wrist, presenting with sensory and motor symptoms in the hand. Diagnosis is based on a combination of clinical findings and electrodiagnostic confirmation. Age = 18 years. Age<65 years Informed consent for participation in the study. Presence of clinical symptoms such as numbness, tingling, or weakness in the affected hand.
Exclusion criteria
Exclusion criteria: History of wrist surgery or nerve reconstruction in the affected hand. Systemic diseases that may mimic CTS symptoms (e.g., uncontrolled diabetes, thyroid disorders). Recent hand or wrist injury within the past 6 months. Use of medications affecting peripheral nerves.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in symptom severity and functional status : based on the Boston Carpal Tunnel Questionnaire (BCTQ). This outcome evaluates the degree of symptom relief (such as numbness, tingling, nocturnal pain, and hand weakness) and the patient’s ability to perform daily tasks (such as writing, buttoning, and holding objects). The BCTQ provides a validated and quantitative assessment of both symptom severity (SSS) and functional status (FSS). Timepoint: 4, 8, and 12 weeks after intervention. Method of measurement: Using the BCTQ, which includes 19 questions divided into two subscales (SSS and FSS). Each item is rated on a 5-point Likert scale, and lower scores indicate better symptom control and hand function. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction in pain : intensity as an indicator of symptomatic improvement following surgery. Pain relief is a key determinant of patient satisfaction and surgical success in carpal tunnel syndrome management. Timepoint: 2, 4, 8, and 12 weeks after intervention. Method of measurement: Using the Visual Analog Scale (VAS), where patients mark their pain intensity on a 10 cm horizontal line ranging from 0 (no pain) to 10 (worst imaginable pain).;Improvement in sensory function of the hand . Restoration of sensory discrimination is essential for hand dexterity and fine motor control. Timepoint: 2, 4, 8, and 12 weeks after intervention. Method of measurement: Assessed using the Two-Point Discrimination (2PD) test with a calibrated caliper. The minimum distance (in millimeters) at which the patient can distinguish two separate points is recorded.;Improvement in neurological clinical tests , including Phalen and Tinel tests, reflecting recovery of median nerve function. Timepoint: 2, 4, 8, and 12 weeks after intervention. Method of measurement: Clinical assessment performed by the investigator; results documented as positive or negative for each test.;Increase in hand muscle strength , including grip and pinch strength, as an indicator of motor recovery and functional improvement. Timepoint: 2, 4, 8, and 12 weeks after intervention. Method of measurement: Measured using a hand dynamometer (in kilograms) for grip strength and a pinch gauge for pinch strength. Higher readings indicate better motor recovery. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactsaeed enayati
Shahroud University of Medical Sciences
Outcome results
None listed