Condition 1: Myositis. Condition 2: Polyarthrosis. Condition 3: Coxarthrosis [arthrosis of hip]. Condition 4: Osteoarthritis of knee. Condition 5: Osteoarthritis of first carpometacarpal joint. Condition 6: Other and unspecified osteoarthritis. Condition 7: Calcification and ossification of muscle. Condition 8: Other disorders of muscle. Condition 9: Disorders of muscle in diseases classified elsewhere. Condition 10: Rheumatoid arthritis with rheumatoid factor. Condition 11: Other rheumatoid art
Conditions
Interventions
Intervention 1: Intervention group: recipients of a topical cream containing therapeutic oils extracted from Achillea millefolium (yarrow) and Tanacetum (tansy) plants.Usage: topical application on th
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Having mild to moderate musculoskeletal pain (involving areas such as the lower back, neck, knee, shoulder, joints, or muscles), with a pain score between 3 and 7 on the Visual Analog Scale (VAS) Stable musculoskeletal pain for at least the past two weeks No use of topical or oral analgesic medications or supplements within the past 72 hours Written informed consent to participate in the study Ability to comply with study procedures (completing forms, regular use of the cream, and attending follow-up visits) No known hypersensitivity or history of allergy to herbal components or topical products
Exclusion criteria
Exclusion criteria: Known allergy or hypersensitivity to medicinal herbs or essential oils Presence of dermatological conditions at the site of cream application Use of topical analgesic or anti-inflammatory products at the pain site within the past 72 hours Use of topical analgesic or anti-inflammatory products at the site of pain within the past 72 hours Presence of systemic diseases affecting pain Pregnancy or breastfeeding Concurrent use of medications affecting pain perception or mood Inability to comply with the study protocol or complete assessment forms Participation in another clinical trial within the past month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome variables in this study include two measures: the intensity of pain in the affected area, assessed using the Visual Analog Scale (VAS) at the beginning and end of the intervention period, and patients’ motor function, evaluated through standardized questionnaires appropriate to the affected region. These two variables are analyzed to determine the efficacy of the herbal cream in reducing musculoskeletal pain and improving physical function in affected patients. Timepoint: Baseline: Before starting the use of the cream. Mid-study: Week 1 and Week 2 . End of intervention: After 2 to 4 weeks of use (depending on pain severity and prescribed duration). Method of measurement: Pain Intensity: Measured using the Visual Analog Scale (VAS). This scale consists of a 10-centimeter horizontal line on which the patient marks their perceived level of pain, ranging from “no pain” (score 0) to “worst imaginable pain” (score 10). Motor Function: Assessed using standardized and validated questionnaires specific to the pain location (e.g., the Oswestry Disability Index for lower back pain, WOMAC for knee pain, or the Neck Disability Index (NDI) for neck pain). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Aghababai Beni
Islamic Azad University
Outcome results
None listed