Comparative Effect of PERIO KIN and TABASSOM Chlorhexidine Gels on Gingival Inflammation

Comparative Evaluation of the Effects of Two Types of Chlorhexidine Gels (PERIO KIN and TABASSOM) as an Adjunctive Therapy on the Control of Periodontal Indices in Patients with Gingivitis

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250720066569N1

Enrollment

Registered

2025-10-27

Start date

2025-11-16

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingivitis. Acute gingivitis

Interventions

Intervention 1: Intervention group: PERIO KIN chlorhexidine gel. This gel contains chlorhexidine and is used topically on the gums. Method of use: twice daily, each time for 10 seconds, for a duration

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 18 years or older Clinical diagnosis of gingivitis with signs of inflammation Gingival Index (GI) equal to or greater than 2 Bleeding on Probing (BOP) in at least 10% of sites No known hypersensitivity to chlorhexidine ASA physical status classification I or maximum II

Exclusion criteria

Exclusion criteria: Consumption of anti-inflammatory or antibiotic drugs within the past three months Pregnancy Smoking

Design outcomes

Primary

Measure	Time frame
Mean change in periodontal probing depth (in millimeters) measured using a Michigan periodontal probe at four sites per tooth. Measurements are taken at three time points: before treatment, one month after treatment, and two months after treatment. Timepoint: Baseline (Before treatment): Two weeks after scaling and root planing. One-month follow-up: One month after starting chlorhexidine gel application. Two-month follow-up: Two months after starting chlorhexidine gel application. Method of measurement: Michigan periodontal probe with millimeter grading.;Mean change in Gingival Index (on a 0-3 scale) assessing gingival inflammation. Evaluations are conducted at three time points: before treatment, one month after treatment, and two months after treatment. Timepoint: Baseline (Before treatment): Two weeks after scaling and root planing. One-month follow-up: One month after starting chlorhexidine gel application. Two-month follow-up: Two months after starting chlorhexidine gel application. Method of measurement: Gingival Index based on criteria defined by Löe and Silness.;Mean change in Papillary Bleeding Index (on a 0-4 scale) measuring gingival bleeding severity. Assessments are performed at three time points: before treatment, one month after treatment, and two months after treatment. Timepoint: Baseline (Before treatment): Two weeks after scaling and root planing. One-month follow-up: One month after starting chlorhexidine gel application. Two-month follow-up: Two months after starting chlorhexidine gel application. Method of measurement: Papillary Bleeding Index based on criteria defined by Saxer and Mühlemann.;Mean change in tooth stain index (based on Lobene Stain Index with a 0-3 scale) measured using the Vita Shade Guide. Assessments are performed at three time points: before treatment, one month after treatment, and two months after treatment. Timepoint: Baseline (Before treatment): Two weeks after scaling and root planing. One-month follow-	—

Measure

Time frame

Mean change in periodontal probing depth (in millimeters) measured using a Michigan periodontal probe at four sites per tooth. Measurements are taken at three time points: before treatment, one month after treatment, and two months after treatment. Timepoint: Baseline (Before treatment): Two weeks after scaling and root planing. One-month follow-up: One month after starting chlorhexidine gel application. Two-month follow-up: Two months after starting chlorhexidine gel application. Method of measurement: Michigan periodontal probe with millimeter grading.;Mean change in Gingival Index (on a 0-3 scale) assessing gingival inflammation. Evaluations are conducted at three time points: before treatment, one month after treatment, and two months after treatment. Timepoint: Baseline (Before treatment): Two weeks after scaling and root planing. One-month follow-up: One month after starting chlorhexidine gel application. Two-month follow-up: Two months after starting chlorhexidine gel application. Method of measurement: Gingival Index based on criteria defined by Löe and Silness.;Mean change in Papillary Bleeding Index (on a 0-4 scale) measuring gingival bleeding severity. Assessments are performed at three time points: before treatment, one month after treatment, and two months after treatment. Timepoint: Baseline (Before treatment): Two weeks after scaling and root planing. One-month follow-up: One month after starting chlorhexidine gel application. Two-month follow-up: Two months after starting chlorhexidine gel application. Method of measurement: Papillary Bleeding Index based on criteria defined by Saxer and Mühlemann.;Mean change in tooth stain index (based on Lobene Stain Index with a 0-3 scale) measured using the Vita Shade Guide. Assessments are performed at three time points: before treatment, one month after treatment, and two months after treatment. Timepoint: Baseline (Before treatment): Two weeks after scaling and root planing. One-month follow-

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Maedeh Tamizi

Esfahan University of Medical Sciences

maedetamizi@dnt.mui.ac.ir+98 31 3366 3338

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026