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Formulation and Standardization of a Hazelnut-Based Oral Semisolid Product and Investigation of Its Effects on Women with Low Sexual Desire

Formulation and Standardization of an Oral Semisolid Preparation Based on Hazelnut (Corylus avellana L.) and Evaluation of Its Effects on Women with Hypoactive Sexual Desire Disorder: A Randomized Double-Blind Controlled Clinical Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250719066546N1
Enrollment
118
Registered
2025-07-24
Start date
2025-08-23
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

female sexual dysfunction. Sexual dysfunction not due to a substance or known physiological condition

Interventions

Intervention 1: Intervention group: A semi-solid preparation made from hazelnut and honey. Fifty-nine patients will receive the hazelnut mixture three times a day, 15 grams per dose. Patients will tak

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Having a husband who is present for at least 50% of the month. Being of reproductive age (18 to 45 years old). Experiencing absent or reduced sexual desire based on interview and according to DSM-IV-TR criteria.

Exclusion criteria

Exclusion criteria: Not having a husband Presence of a serious medical condition (any illness requiring medication during the study period) History of genital or breast cancer Presence of major depression or other psychiatric disorders under psychiatric treatment (assessed via the Patient Health Questionnaire-9) Menopause Definite intention to divorce Pregnancy Breastfeeding Diabetes Drug allergy

Design outcomes

Primary

MeasureTime frame
Score of Sexual Function Index in the FSFI Questionnaire, Depression Score in the HPQ-9 Questionnaire, and Uterine Temperament and Body Temperament in the Uterine and Body Temperament Questionnaire. Timepoint: 8 weeks. Method of measurement: Female Sexual Function Index (FSFI), QuestionnaireHPQ-9, uterine Temperament and Body Temperament Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoja Rahimi

Tehran University of Medical Sciences

rojarahimi@gmail.com+98 21 8897 4535

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026