Comparison of the effect of ketamine-atropine and midazolam combination compared to dexmedetomidine-atropine and midazolam combination on the sedation level of children undergoing bone marrow biopsy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250719066544N1

Enrollment

Registered

2025-07-26

Start date

2025-07-26

Completion date

Unknown

Last updated

2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with hematological and oncological diseases.

Interventions

Intervention group: Children undergoing bone marrow biopsy with hematological and oncological diseases hospitalized in Qom Province Pediatric Hospital.

Eligibility

Sex/Gender

All

Age

1 Years to 8 Years

Inclusion criteria

Inclusion criteria: Children who are candidates for bone marrow biopsy Absence of congenital heart and respiratory disease

Exclusion criteria

Exclusion criteria: Children with congenital cardio-respiratory diseases Clinical signs of productive cough Fever Wheezing or crackles in the lungs Parental disapproval

Design outcomes

Primary

Measure	Time frame
Sedation level. Timepoint: 2, 5, 10, 15 minutes after administering the medications and after the procedure. Method of measurement: Ramsay and Rass Sedation Criteria.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactreza aminnejad

Ghoum University of Medical Sciences

r.aminnejad@yahoo.com+98 25 3612 2000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026