Adhesive Capsulitis (Frozen Shoulder), Idiopathic and Diabetic. Adhesive capsulitis of shoulder
Conditions
Interventions
Intervention 1: Intervention group: Single intra-articular injection of 4 mL platelet-rich plasma (activated with thrombin, 1:10) mixed with 4 mL of 2% lidocaine and diluted with distilled water to a
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Age
30 Years to 78 Years
Inclusion criteria
Inclusion criteria: Age between 30 and 75 years; unilateral frozen shoulder diagnosed by physical examination and clinical evaluation; shoulder pain persisting for at least one month; loss of at least one-third of the range of motion in various shoulder movements; normal shoulder joint radiography; normal neurological examination of the proximal upper limb; and no prior pain relief interventions for the affected shoulder.
Exclusion criteria
Exclusion criteria: History of previous treatments aimed at reducing shoulder pain, such as intra-articular injections; unwillingness to continue participation in the study; any intra-articular pathology of the glenohumeral joint or shoulder pain due to other causes; history of trauma or shoulder surgery; clinical evidence of Sudeck’s atrophy syndrome; injection in the affected shoulder joint within the past six months; use of non-steroidal anti-inflammatory drugs in the last seven days; presence of blood disorders or current antiplatelet or anticoagulant treatment; presence of thyroid or lung disorders, particularly emphysema and chronic bronchitis; neoplastic disorders; pregnancy or breastfeeding; uncontrolled diabetes; neurological, rheumatological, malignant, or immunodeficiency diseases; history of drug or alcohol use or addiction; and cervical radiculopathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in shoulder pain, disability (SPADI, VAS), and range of motion measured at baseline, 4 weeks, and 8 weeks after treatment. Timepoint: Baseline, 4 weeks, and 8 weeks after intervention. Method of measurement: Shoulder Pain and Disability Index questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in pain intensity score measured by the Visual Analogue Scale from baseline to 8 weeks after intervention. Timepoint: Baseline, 4 weeks, and 8 weeks after intervention. Method of measurement: Measured using a goniometer for shoulder range of motion. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Saeed Enayati
Islamic Azad University
Outcome results
None listed