Oral lichenplanus. Diseases of the skin and subcutaneous tissue, Papulosquamous disorders
Conditions
Interventions
Intervention 1: 5 ml of a mouthwash formulated with dexamethasone 0.1 mg/ml + fluconazole 2 mg/ml, 3 times a day for 3 weeks. Intervention 2: Control group: Mix a 0.5 mg tablet with 30 drops of nystat
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Adults over 18 and under 65 years of age People who are prescribed mouthwash due to the number or extent of pathological lesions, as approved by a specialist, and the severity of the lesions is equal to two or more according to the Thongprsom criteria. Those who have informed consent to participate in the study
Exclusion criteria
Exclusion criteria: Severe problems due to systemic diseases (more than two according to the ASA classification). People who are unable to rinse their mouth with topical corticosteroids due to systemic or medication reasons. People who have severe dysplasia based on the pathology results People who, for whatever reason, do not wish to continue participating in the project. People who have allergies to the drug or a history of allergies to other components of the formulation. Topical and systemic use of corticosteroid medications in the last 3 weeks Pregnant and breastfeeding women Immunocompromised patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of oral lichen planus lesions. Timepoint: At the beginning of the study /1 week/2 weeks/3 weeks. Method of measurement: Thongprosam.;Pain and burning. Timepoint: At the beginning of the study /1 week/2 weeks/3 weeks. Method of measurement: Visual Analogue Scale (VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Treatment Satisfaction. Timepoint: End of the third week. Method of measurement: Treatment Satisfaction Questionnaire for Medication-9 (TSQM-9). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ehsan Jannatabadi
Mashhad University of Medical Sciences
Outcome results
None listed