Gingivitis. Chronic gingivitis, plaque induced
Conditions
Interventions
Intervention 1: Intervention group: Participants receive the herbal mouthwash containing hydroalcoholic extract of Cyperus rotundus (5%), thyme (3%), and bitter orange (2%) for 4 weeks, and use the mo
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Age: 18 to 50 years Diagnosis of mild to moderate gingivitis based on the Gingival Index (GI) score ranging from 1 to 2 Presence of at least 20 natural teeth Absence of systemic diseases known to significantly affect periodontal health (e.g., uncontrolled diabetes mellitus, autoimmune or immunodeficiency disorders) No use of antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), or any other medications known to influence gingival status within the past 3 months No known hypersensitivity to Cyperus rotundus, Thymus vulgaris (Thyme), Citrus aurantium (Bitter orange), or chlorhexidine Ability and willingness to comply with the study protocol and provide written informed consent
Exclusion criteria
Exclusion criteria: Presence of clinical attachment loss > 3 mm or a diagnosis of periodontitis Pregnancy or Lactation Receipt of professional periodontal treatment (e.g., scaling and root planing or periodontal surgery) within the past 6 months Current or recent use of cigarettes, hookah, or any other tobacco products Use of narcotic drugs or psychoactive medications Presence of active oral lesions (e.g., recurrent aphthous ulcers or severe mucosal diseases) that may interfere with the intervention or outcome assessment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plaque Index. Timepoint: Measurement of the Plaque Index at the beginning of the study (before starting the intervention) and at two and four weeks after starting mouthrinse use. Method of measurement: The Plaque Index is assessed using the Silness and Löe method.;Gingival Bleeding Index. Timepoint: Measurement of the Gingival Bleeding Index at the beginning of the study (before starting the intervention) and at two and four weeks after starting mouthrinse use. Method of measurement: The Gingival Bleeding Index is assessed using the Silness and Löe method.;Gingival Index. Timepoint: Measurement of the Gingival Index at the beginning of the study (before starting the intervention) and at two and four weeks after starting mouthrinse use. Method of measurement: The Gingival Index is assessed using the Silness and Löe method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMojtaba Ziaee
Tabriz University of Medical Sciences
Outcome results
None listed