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Comparison of the Effects of Fentanyl and Remifentanil on Hemodynamic Changes in Children Undergoing Tonsillectomy and Adenoidectomy

Comparison the Effect of Fentanyl and Remifentanil on Hemodynamic Changes in Pediatrics Undergoing Tonsil and Adenoid Surgery at Shafa Hospital, Kerman University of Medical Sciences, in 2024-2025

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250713066479N1
Enrollment
60
Registered
2025-07-18
Start date
2025-07-14
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tonsillectomy and Adenoidectomy.

Interventions

Intervention 1: Intervention group: Fentanyl-Propofol Regimen • Pre-medication: Oral midazolam 0.05 mg/kg, 30 minutes before entering the operating room • Induction of anesthesia: • Fentanyl 1 µg/kg

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 12 Years

Inclusion criteria

Inclusion criteria: Age 3 to 12 years ASA class I or II no history of allergy to the drugs used in the study no underlying cardiac, pulmonary, renal, or hepatic diseases informed consent obtained from the parents for participation in the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Systolic Blood Pressure. Timepoint: upon entry to the operating room, 2 minutes after drug administration, 1, 5, and 10 minutes after intubation, and at the end of surgery. Method of measurement: using a standard non-invasive blood pressure monitor.;Diastolic Blood Pressure. Timepoint: upon entering the operating room, 2 minutes after drug administration, and at 1, 5, and 10 minutes after intubation, and at the end of surgery. Method of measurement: tandard non-invasive blood pressure monitoring device.;Mean Arterial Pressure. Timepoint: upon entering the operating room, 2 minutes after drug administration, and at 1, 5, and 10 minutes after intubation, and at the end of surgery. Method of measurement: Mean arterial pressure measured either directly using a non-invasive monitor or calculated using the formula.;Heart Rate. Timepoint: upon entering the operating room, 2 minutes after drug administration, and at 1, 5, and 10 minutes after intubation, and at the end of surgery. Method of measurement: Heart rate (beats per minute).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReyhaneh Komasi

Kerman University of Medical Sciences

mohammadmahdi8754@yahoo.com+98 34 3132 5700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026