Osteoarthritis. Osteoarthritis of knee
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with advanced osteoarthritis or severe knee joint destruction who require knee replacement surgery in 2025. Aged between 50 and 75 years. Have no history of previous surgery on the knee in question. Informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: Patients with severe underlying diseases such as active cancer. Coagulation disorders. Active infection. Sensitivity to radiation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Component alignment. Timepoint: Before surgery and six months after surgery. Method of measurement: Radiology photo. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Before surgery and six months after surgery. Method of measurement: Visual Analogue Scale.;Osteoarthritis-related symptoms and physical disability, providing a composite assessment of treatment effect. Timepoint: Before surgery and six months after surgery. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis Index.;Range of Motion. Timepoint: Before surgery and six months after surgery. Method of measurement: Measured using a standardized goniometer by a trained physiotherapist or physician.;Assess knee function and anterior knee pain. Timepoint: Before surgery and six months after surgery. Method of measurement: Kujala Anterior Knee Pain Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Mashhad University of Medical Sciences