The effect of dexamethasone on airway edema reduction

The effect of dexamethasone on airway edema reduction and extubation success in patients with head trauma admitted to the intensive care unit

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250710066438N1

Enrollment

Registered

2025-07-25

Start date

2025-08-23

Completion date

Unknown

Last updated

2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

airway edema.

Interventions

Intervention 1: Intervention group: Patients in this group receive intravenous dexamethasone at an initial dose of 8 mg every 8 hours. This process continues for 48 hours. The drug solution is prepare

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients admitted to the intensive care unit with a history of traumatic brain injury Requirement for endotracheal intubation and mechanical ventilation for a minimum duration of 24 hours Eligibility for dexamethasone administration was determined by the treating physician. Written informed consent was obtained from the patient or legal guardian before enrollment in the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Airway edema. Timepoint: Length of stay. Method of measurement: Endotracheal tube removal success.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Nasrollahi

Bandare-abbas University of Medical Sciences

Fatemeh.Nasrollahi@hums.ac.ir+98 916 226 4220

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026