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Evaluation effect of Intravenous Magnesium Sulfate on pain rate afterL4,L5,S1 lumbar spine surgeryin clinical trial

Evaluation effect of Intravenous Magnesium Sulfate on pain rate afterL4,L5,S1 lumbar spine surgeryin clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250630066304N1
Enrollment
80
Registered
2025-07-13
Start date
2025-07-22
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar disc surgery L4, L5, S1. Intervertebral disc disorders with radiculopathy, lumbar region

Interventions

Intervention 1: Intervention group:Magnesium sulfate is injected once into the patient at a dose of 50 mg/kg of body weight half an hour before the operation from Darupakhsh Pharmaceutical Company, ma

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Confirming the diagnosis with a physical examination, CT scan, and MRI Patient's willingness to participate in the study and obtaining informed consent Candidate for non-emergency discectomy surgery People under 50 years old People with normal kidney function People with no history of heart problems

Exclusion criteria

Exclusion criteria: The patient's unwillingness at any time to continue participating in the study Emergency discectomy surgery Known allergy to one of the study drugs Use of narcotic painkillers up to 12 hours before the intervention Alcohol or drug abuse

Design outcomes

Primary

MeasureTime frame
Pain intensity. Timepoint: After surgery and before leaving recovery, 4 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
The amount of nausea and vomiting. Timepoint: After surgery and before leaving recovery, 4 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamira Sobhani

Mazandaran University of Medical Sciences

Ssobhani1983@gmail.com+98 11 3336 1700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026