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Quantitative assessment and modeling of balance and gait recovery patterns in patients with Multiple Sclerosis for designing therapeutic protocols based on antigravity treadmill training

Quantitative assessment and modeling of balance and gait recovery patterns in patients with Multiple Sclerosis for designing therapeutic protocols based on antigravity treadmill training

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250629066292N2
Enrollment
36
Registered
2025-07-23
Start date
2025-08-11
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis - MS disease. Multiple sclerosis

Interventions

Intervention 1: Intervention group: Participants will undergo a modern skill acquisition rehabilitation program using an anti-gravity treadmill for 30 minutes per session, 3 times a week, for a total

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Suffering from moderate to severe MS Ability to stand and take at least 3 steps independently. Age between 18 and 50 years. Informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: Heart or vascular problems that do not allow for sports activities. Serious problems in the knee or hip joints that prevent the use of an anti-gravity treadmill. The patient's lack of cooperation during the treatment period. Severe MS attacks that cause disability or hospitalization of the patient.

Design outcomes

Primary

MeasureTime frame
Stiffness. Timepoint: Before the start of treatment, After one month of receiving the treatment program, Immediately after completing the treatment program, One month after the end of treatment(Follow-up). Method of measurement: Neuromuscular rehabilitation robot device.;Center of pressure fluctuations. Timepoint: Before the start of treatment, After one month of receiving the treatment program, Immediately after completing the treatment program, One month after the end of treatment(Follow-up). Method of measurement: Force plate.;Timed Up and Go Test. Timepoint: Before the start of treatment, After one month of receiving the treatment program, Immediately after completing the treatment program, One month after the end of treatment(Follow-up). Method of measurement: Stopwatch.

Secondary

MeasureTime frame
Step length. Timepoint: Before the start of treatment (Baseline), After one month of receiving the treatment program (Mid-point), Immediately after completing the treatment program (Post-treatment), One month after the end of treatment (Follow-up). Method of measurement: Using marker positions in the motion capture lab.;Walking speed. Timepoint: Before the start of treatment (Baseline), After one month of receiving the treatment program (Mid-point), Immediately after completing the treatment program (Post-treatment), One month after the end of treatment (Follow-up). Method of measurement: Using marker positions in the motion capture lab.;Ankle joint angles. Timepoint: Before the start of treatment (Baseline), After one month of receiving the treatment program (Mid-point), Immediately after completing the treatment program (Post-treatment), One month after the end of treatment (Follow-up). Method of measurement: Using marker positions in the motion capture lab.;Fluctuations in the center of static pressure. Timepoint: Before the start of treatment (Baseline), After one month of receiving the treatment program (Mid-point), Immediately after completing the treatment program (Post-treatment), One month after the end of treatment (Follow-up). Method of measurement: Force plate.;Active ankle range of motion. Timepoint: Before the start of treatment (Baseline), After one month of receiving the treatment program (Mid-point), Immediately after completing the treatment program (Post-treatment), One month after the end of treatment (Follow-up). Method of measurement: Neuromuscular rehabilitation robot displacement recording sensor.;Maximum voluntary contraction force. Timepoint: Before the start of treatment (Baseline), After one month of receiving the treatment program (Mid-point), Immediately after completing the treatment program (Post-treatment), One month after the end of treatment (Follow-up). Method of measurement: Torque recording sensor for neuromuscular rehabilitatio

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Mehdi Mirbagheri

Tehran University of Medical Sciences

mehdi.northwestern@gmail.com02164051

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026