chronic kidney disease. Chronic kidney disease (CKD)
Conditions
Interventions
Intervention 1: Intervention group: One synbiotic capsule will be administered daily for 12 weeks, containing the following probiotics: Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus acid
Sponsors
Yasouj University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients aged 18 to 60 chronic kidney disease (CKD) - GFR between 30 and 60 (Stage 3 and 4 CKD) - Not receiving renal replacement therapy
Exclusion criteria
Exclusion criteria: _Current Probiotic Use in Specific Populations - Pregnant women - Kidney transplant patients - Patients with gastrointestinal disorders (dysphagia, gastrectomy, irritable bowel syndrome) - Patients with active cancer - Individuals with psychiatric disorders undergoing treatment - Paralyzed or bedridden individuals - Patients with HIV/AIDS, tumors, or autoimmune diseases - Patients receiving treatment with antibiotics, NSAIDs, or corticosteroids
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glomerular Filtration Rate. Timepoint: At baseline and at 12 weeks post-intervention. Method of measurement: CKD-EPI.;Quality of life. Timepoint: At baseline and at 12 weeks post-intervention. Method of measurement: Kidney disease quality of life; KDQOL-SFTM 1.3. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamad Kheirkhah
Yasouj University of Medical Sciences
Outcome results
None listed