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Effect of Dexmedetomidine on Hemodynamic Stability and Opioid Requirement in Pulmonary Hydatid Cyst Surgery

The Effect of Dexmedetomidine on Hemodynamic Stability and Opioid Requirement in Patients Undergoing Pulmonary Hydatid Cyst Surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250626066260N1
Enrollment
40
Registered
2025-11-21
Start date
2026-02-20
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Hydatid Cyst. Echinococcus granulosus infection, unspecified

Interventions

Intervention 1: Intervention group: Includes patients who, after induction of anesthesia, receive dexmedetomidine initially at a dose of 1 µg/kg over 10 minutes, followed by 0.5 µg/kg/h via intravenou

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 65 years Candidate for unilateral pulmonary hydatid cyst surgery (via thoracotomy or VATS) Physical status ASA class I or II Written informed consent to participate in the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Systolic and diastolic blood pressure. Timepoint: Before induction of anesthesia; after surgical incision; every fifteen minutes during surgery; in the recovery room. Method of measurement: Measurement of systolic and diastolic blood pressure using invasive and noninvasive automatic blood pressure monitor.;Heart rate. Timepoint: Before induction of anesthesia; after surgical incision; every fifteen minutes during surgery; in the recovery room. Method of measurement: Measurement of heart rate using an electrocardiographic cardiac monitor.;Total intraoperative opioid consumption. Timepoint: From the beginning of anesthesia induction until the end of the surgical procedure. Method of measurement: Calculation of the total opioid dose based on values recorded by the anesthesia team in the anesthesia record.

Secondary

MeasureTime frame
Postoperative pain score measured by the Visual Analogue Scale. Timepoint: In the recovery room; two hours after surgery; four hours after surgery. Method of measurement: Measurement using a ten-centimeter Visual Analogue Scale for pain assessment.;Postoperative nausea and vomiting. Timepoint: In the recovery room; two hours after surgery; four hours after surgery. Method of measurement: Clinical observation and documentation of nausea and vomiting events by the recovery room nurse.;Sedation level assessed by the Ramsay Sedation Scale. Timepoint: In the recovery room; thirty minutes after admission to recovery. Method of measurement: Assessment using the Ramsay Sedation Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactVahid Nourbakhsh

Mashhad University of Medical Sciences

vhn041@gmail.com+98 915 834 0408

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026