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Investigating of the changes in the functional and structural brain connectivities due to electromyographic biofeedback training related for hand grasping in hemiparetic children using processing of the EEG signals and the DTI images

Investigating of the changes in the functional and structural brain connectivities due to electromyographic biofeedback training related for hand grasping in hemiparetic children using processing of the EEG signals and the DTI images

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250624066242N3
Enrollment
5
Registered
2026-05-14
Start date
2026-05-19
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral palsy. Spastic hemiplegic cerebral palsy

Interventions

Intervention group: Children with unilateral cerebral palsy (spastic hemiplegia) will participate in therapeutic intervention sessions combined with electromyographic biofeedback and stimulation of ha

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 16 Years

Inclusion criteria

Inclusion criteria: Children with unilateral cerebral palsy or spastic hemiplegia will be selected based on a specialist diagnosis. Children over 5 years of age will be included in the study.

Exclusion criteria

Exclusion criteria: If the patient's grade is determined to be severe based on criteria such as gross motor function, they will not be included in the study. Children with severe visual and hearing impairments will be excluded from the study. If children are unable to perform the task due to cognitive or behavioral impairments, they will be excluded from the study. If there are orthopedic defects in the hands that prevent the desired movement, the child will not be included in the study.

Design outcomes

Primary

MeasureTime frame
All hand movements. Timepoint: 3 months. Method of measurement: Fugl-Meyer Assessment and Ashworth test.

Secondary

MeasureTime frame
The analysis of brain dynamic changes conducted using EEG signals and the evaluation of structural brain connectivity changes using DTI. For this purpose, five pediatric patients will be selected. After completing the intervention exercises, the effectiveness of the motor–cognitive training delivered through the device will be evaluated.The first assessment will be the Ashworth test, which measures the level of wrist muscle spasticity. Timepoint: Five patients, each undergoing 15 training sessions. Method of measurement: The level of wrist muscle spasticity will be assessed using the Ashworth test. The results will be obtained before the start of the intervention and after completion of the 15 sessions and will then be compared to determine the extent of improvement in cognitive and hand motor functions.;The analysis of brain dynamic changes conducted using EEG signals and the evaluation of structural brain connectivity changes using DTI. For this purpose, five pediatric patients will be selected. In the next stage, the Fugl–Meyer Assessment will be used to evaluate hand motor function. Timepoint: Five patients, each undergoing 15 training sessions. Method of measurement: Fugl–Meyer Assessment of the upper extremity will be administered to evaluate motor abilities. The results will be obtained before the start of the intervention and after completion of the 15 sessions and will then be compared to determine the extent of improvement in cognitive and hand motor functions.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Akhondian Yazdi

Mashhad University of Medical Sciences

Akhondianj@mums.ac.ir+98 51 3844 0350

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026