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Study of the combined effect of antibiotics on the clinical and cosmetic characteristics after horizontal dental bone reconstruction surgery.

Evaluation of the Effect of antibiotic combination of metronidazole gel and tetracycline ointment on clinical characteristics of soft tissue after horizontal ridge reconstruction surgeries

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250623066230N1
Enrollment
50
Registered
2025-11-03
Start date
2025-10-22
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral and dental diseases. Presence of tooth-root and mandibular implants

Interventions

Intervention 1: Intervention group: The antibiotic combination of topical metronidazole gel with appropriate concentration (usually 0.75% to 1%) and topical tetracycline ointment with 3% concentration

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: The amount of bone required for reconstruction is the same on both sides. Patients who are candidates for tooth extraction on both sides of the jaw Partially edentulous patients on both sides of the jaw

Exclusion criteria

Exclusion criteria: Smokers Pregnant women Presence of pathology or tumor at the surgical site Presence of systemic diseases such as uncontrolled diabetes or head and neck radiotherapy Avoid taking medications that affect the inflammatory process, such as corticosteroids.

Design outcomes

Primary

MeasureTime frame
Symptoms after surgery. Timepoint: 1, 3, and 7 days after surgery. Method of measurement: Redness, edema, ecchymosis, discharge from the wound, approximation indices(REEDA).;Reducing pain after surgery. Timepoint: 1, 3, and 7 days after surgery. Method of measurement: Visual analogue scale indices(VAS).

Secondary

MeasureTime frame
Successful treatment after implant placement. Timepoint: 4 months later. Method of measurement: Imaging and clinical evaluation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Reza Babaloo

Tabriz University of Medical Sciences

amirrezababaloo@yahoo.com+98 914 311 6342

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026