The effect of dexmedetomidine on the quality of sleep and reducing delirium after major urological surgeries

Evaluation and comparison of the effect of dexmedetomidine on the quality of sleep and reducing delirium after major urological surgeries

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250623066224N1

Enrollment

Registered

2025-07-15

Start date

2025-08-06

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Genitourinary. postprocedural disorder of genitourinary system, unspecified

Interventions

Intervention 1: Intervention group: The intervention group will receive 0.3 µg/kg of dexmedetomidine (DEX) diluted in normal saline, administered over 10 minutes during the final 20 minutes of the sur

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Inclusion criteria

Inclusion criteria: Age between 50 to 90 ASA I &II BMI lower than 35

Exclusion criteria

Exclusion criteria: Uncontrolled systemic diseases (such as diabetes, hypertension, and heart disease) Addiction Allergy to DEX

Design outcomes

Primary

Measure	Time frame
Sleep quality score based on the Athens Insomnia Scale (AIS). Timepoint: Sleep quality score at 24 and 48 hours postoperatively. Method of measurement: The Athens Insomnia Scale (AIS).;Delirium score assessed using the Confusion Assessment Method (CAM). Timepoint: Delirium score at 24 and 48 hours postoperatively. Method of measurement: The Confusion Assessment Method (CAM).;Incidence of complications including bradycardia and hypotension, according to clinical findings. Timepoint: Assessment of bradycardia and hypotension at 0, 6, 12, and 24 hours after surgery. Method of measurement: Automated vital signs monitor.	—

Measure

Time frame

Sleep quality score based on the Athens Insomnia Scale (AIS). Timepoint: Sleep quality score at 24 and 48 hours postoperatively. Method of measurement: The Athens Insomnia Scale (AIS).;Delirium score assessed using the Confusion Assessment Method (CAM). Timepoint: Delirium score at 24 and 48 hours postoperatively. Method of measurement: The Confusion Assessment Method (CAM).;Incidence of complications including bradycardia and hypotension, according to clinical findings. Timepoint: Assessment of bradycardia and hypotension at 0, 6, 12, and 24 hours after surgery. Method of measurement: Automated vital signs monitor.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadTaha Rahimipour

Yazd University of Medical Sciences

taharahimipour@yahoo.com+98 35 3821 5311

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026