The effect of dexamethasone in improving sleep quality and reducing delirium in elderly patients after major urological surgeries

Evaluation of the effect of dexamethasone in improving sleep quality and reducing delirium in elderly patients after major urological surgeries

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250623066223N1

Enrollment

Registered

2025-07-15

Start date

2025-08-06

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Genitourinary. postprocedural disorder of genitourinary system, unspecified

Interventions

Intervention 1: Intervention group: The intervention group will receive 8 mg (2 mL) dexamethasone intravenously after induction of anesthesia. Intervention 2: The control group will receive 2 mL of no

Eligibility

Sex/Gender

Male

Age

50 Years to No maximum

Inclusion criteria

Inclusion criteria: Men over 50 ASA I &II No alcohol consumption and substance abuse

Exclusion criteria

Exclusion criteria: Presence of Adrenal diseases Uncontrolled systemic diseases Use of psychotropic medications or a history of psychiatric disorders

Design outcomes

Primary

Measure	Time frame
Sleep quality score based on the Athens Insomnia Scale (AIS). Timepoint: Sleep quality score at 24 and 48 hours postoperatively. Method of measurement: The Athens Insomnia Scale (AIS).;Delirium score assessed using the Confusion Assessment Method (CAM). Timepoint: Delirium score at 24 and 48 hours postoperatively. Method of measurement: The Confusion Assessment Method (CAM).;Incidence of complications including elevated blood pressure and heart rate (based on clinical findings). Timepoint: Assessment of hypertension and elevated heart rate at 0, 6, 12, and 24 hours after surgery. Method of measurement: Automated vital signs monitor.;Hyperglycemia defined as random blood glucose levels exceeding 200 mg/dL. Timepoint: Evaluation of hyperglycemia defined as random blood glucose >200 mg/dL at 0 and 24 hours postoperatively. Method of measurement: Standard glucometer.	—

Measure

Time frame

Sleep quality score based on the Athens Insomnia Scale (AIS). Timepoint: Sleep quality score at 24 and 48 hours postoperatively. Method of measurement: The Athens Insomnia Scale (AIS).;Delirium score assessed using the Confusion Assessment Method (CAM). Timepoint: Delirium score at 24 and 48 hours postoperatively. Method of measurement: The Confusion Assessment Method (CAM).;Incidence of complications including elevated blood pressure and heart rate (based on clinical findings). Timepoint: Assessment of hypertension and elevated heart rate at 0, 6, 12, and 24 hours after surgery. Method of measurement: Automated vital signs monitor.;Hyperglycemia defined as random blood glucose levels exceeding 200 mg/dL. Timepoint: Evaluation of hyperglycemia defined as random blood glucose >200 mg/dL at 0 and 24 hours postoperatively. Method of measurement: Standard glucometer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactElahe Zeinali

Yazd University of Medical Sciences

eliela.zn05@gmail.com+98 35 3821 5311

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026