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Comparison of the effects of intermittent and infusion ephedrine in cesarean section under spinal anesthesia

Comparing the preventive administration of intermittent ephedrine and infusion on hemodynamics of cesarean patients undergoing spinal anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250609066142N1
Enrollment
81
Registered
2025-11-05
Start date
2025-09-23
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood pressure during labor. Elevated blood-pressure reading, without diagnosis of hypertension

Interventions

Intervention 1: Intervention group: Received ephedrine bolus. In this group, 50 mg of ephedrine in 100 cc of normal saline will be injected over 30 to 60 minutes. Intervention 2: Intervention group: R

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age between 15 and 45 years old Candidate for cesarean section with spinal anesthesia No systemic diseases

Exclusion criteria

Exclusion criteria: Allergy to anesthetic medication

Design outcomes

Primary

MeasureTime frame
Blood pressure during labor: In all patients, before the start of spinal anesthesia, venipuncture is performed in the upper limb with an angiocet number 18, and 1500 ml of Ringer's solution is injected, and the patients' vital signs (systolic, diastolic blood pressure, and heart rate) are recorded. Timepoint: Vital signs will be monitored every 3 minutes until delivery, every 5 minutes until the incision is closed, and every 10 minutes until recovery. Method of measurement: Digital pressure gauge.

Secondary

MeasureTime frame
Vomiting. Timepoint: From the start of spinal anesthesia to the end of recovery. Method of measurement: Observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Baratee

Mazandaran University of Medical Sciences

fatemeh.baratee79@gmail.com+98 11 3304 4030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026