effect of probiotic supplementation in transplant patients

Investigating the effect of probiotic supplementation on progression of Carotid intima-media thickness after kidney transplantation, a triple blinded clinical trial study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250609066136N1

Enrollment

Registered

2025-08-12

Start date

2025-09-23

Completion date

Unknown

Last updated

2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: kidney transplant. Condition 2: Atherosclerosis. Kidney transplant status Occlusion and stenosis of carotid artery

Interventions

Intervention 1: Intervention group: Will receive one probiotic supplement daily produced by Zist Tahmir Company. This supplement contains the following bacterial strains: Lactobacillus rhamnosus Lacto

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: First kidney transplant at least three months after transplantation no impairment in allograft function prior to study entry

Exclusion criteria

Exclusion criteria: Multiple transplants graft loss during the first three months hepatitis smoking, diabetes pregnancy history of cardiovascular diseas? graft rejection before and after study malignancy liver cirrhosis

Design outcomes

Primary

Measure	Time frame
Intima- media carotid thickness. Timepoint: before and 3 months after intervention initiation. Method of measurement: Doppler sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomaye-Sadat Heidari

Shahid Beheshti University of Medical Sciences

somayesadat_heidary@yahoo.com+98 21 2259 4197

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026