Comparison of Two Pain Control Methods After Chest Surgery: Anterior Rib Muscle Block Injection versus Continuous Infusion of the Anesthetic Drug Ketodex

Comparison serratus anterior block versus intraoperative continuous infusion of ketodex in acute pain management of thoracotomy-Randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250609066132N1

Enrollment

Registered

2025-07-07

Start date

2025-07-21

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracotomy. Traumatic pneumothorax

Interventions

Intervention 1: Intervention Group (Serratus Anterior Block - SAB):Participants in the SAB group will receive an ultrasound-guided serratus anterior block immediately after anesthesia induction. Using

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult patients aged 18 years and older Candidates scheduled for elective thoracotomy Ability to provide informed and voluntary consent to participate in the study

Exclusion criteria

Exclusion criteria: Allergy to study medications Coagulation disorders or use of anticoagulants Psychiatric or cognitive disorders affecting informed consent Chronic use of opioids or analgesics History of previous chest surgery

Design outcomes

Primary

Measure	Time frame
Nausea and Vomiting. Timepoint: Immediately after surgery, 2, 4, 8, 12, and 24 hours post-op. Method of measurement: PONV score (presence/absence).;Arterial Oxygen Saturation (O2 Sat). Timepoint: Upon arrival to OR, then every 15 minutes until end of surgery and in recovery. Method of measurement: Based on the patient's medical record.;Pain. Timepoint: Immediately after surgery, 1, 6, 12, and 24 hours post-op. Method of measurement: VAS scale (pain score).;Patient Satisfaction with Pain Management. Timepoint: Postoperative period. Method of measurement: Likert scale.;Prescribed Morphine Dose. Timepoint: First 24 hours post-op. Method of measurement: Total morphine dose (mg).	—

Measure

Time frame

Nausea and Vomiting. Timepoint: Immediately after surgery, 2, 4, 8, 12, and 24 hours post-op. Method of measurement: PONV score (presence/absence).;Arterial Oxygen Saturation (O2 Sat). Timepoint: Upon arrival to OR, then every 15 minutes until end of surgery and in recovery. Method of measurement: Based on the patient's medical record.;Pain. Timepoint: Immediately after surgery, 1, 6, 12, and 24 hours post-op. Method of measurement: VAS scale (pain score).;Patient Satisfaction with Pain Management. Timepoint: Postoperative period. Method of measurement: Likert scale.;Prescribed Morphine Dose. Timepoint: First 24 hours post-op. Method of measurement: Total morphine dose (mg).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactShadi Oboodi

Shiraz University of Medical Sciences

sh_oboudi@yahoo.com+98 71 3628 1460

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026