Overweight and obesity. Overweight and obesity
Conditions
Interventions
Intervention 1: Botox group: After about 6 to 12 hours of fasting, the patient undergoes endoscopy under anesthesia and Botox is injected into the stomach. First, a vial of 500 units of BTX-A from the
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Body mass index equal to or greater than 30 kg/m2 and less than 39.9 Body mass index between 27 and 29.9 kg/m2 in the presence of comorbidities associated with abnormal weight who had not experienced at least five percent weight loss over a six-month period with lifestyle interventions
Exclusion criteria
Exclusion criteria: Pregnancy or breastfeeding Known history of allergy to botulinum toxin A History of angina pectoris, myocardial infarction, cerebral ischemia within the previous three months Liver and kidney failure Myopathy or neuromuscular disorder Peptic ulcer during endoscopy History of bariatric surgeries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient weight. Timepoint: Measurement of patient weight at the beginning of the study (before the start of the intervention) and 14, 28, 60, and 120 days after the intervention. Method of measurement: Digital scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Reza Najarzade
Mashhad University of Medical Sciences
Outcome results
None listed