Comparing the effect of Clindamycin and Cefaloxin versus Clindamycin and Cefazolin antibiotic regimens in reducing infection cases after elective cesarean section

Comparing the effect of Clindamycin and Cefaloxin versus Clindamycin and Cefazolin antibiotic regimens in reducing infection cases after elective cesarean section in patients with BMI>30

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250607066094N1

Enrollment

110

Registered

2025-08-07

Start date

2025-03-21

Completion date

Unknown

Last updated

2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical Site Infection.

Interventions

Intervention group: The first group, in addition to the routine prophylactic regimen (cefazolin) during surgery and clindamycin tablets after transfer to the ward and immediately after they are able t

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women with a gestational age of over 38 weeks who undergo elective cesarean section. BMI>30

Exclusion criteria

Exclusion criteria: Emergency cesarean section (meconium tic, ruptured membranes, preeclampsia, etc.) Immune-compromised patients, patients with renal failure Patients who are allergic to cefazolin or clindamycin or cephalexin Patients who have recently received an antibiotic regimen within the last three months Diabetic patients or a history of GDM

Design outcomes

Primary

Measure	Time frame
Surgical Site Infection. Timepoint: Day of operation, day of discharge, one week after discharge. Method of measurement: Based on SIRS Criteria.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAnousheh Salehi

Bandare-abbas University of Medical Sciences

hospital.drshariati@gmail.com+98 939 397 8737

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026