Effect of Photobiomodulation on Pain Reduction After Miniscrew Placement in Orthodontics

Investigating the Effectiveness of Photobiomodulation Therapy on Pain Reduction After Miniscrew Placement in Orthodontic Patients: A Randomized Clinical Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250605066076N1

Enrollment

Registered

2025-06-10

Start date

2025-06-22

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain following miniscrew placement in orthodontic treatment.

Interventions

Intervention 1: Intervention group: Photobiomodulation therapy using a diode laser with a wavelength of 940 nanometers, power of 300 milliwatts, and energy density of 31.7 joules per square centimeter

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients requiring miniscrew placement during orthodontic treatment No prior orthodontic treatment before the study No radiographic evidence of bone loss No active dental caries No periodontal diseases Adequate oral hygiene

Exclusion criteria

Exclusion criteria: Hypersensitivity to laser light Pregnancy

Design outcomes

Primary

Measure	Time frame
Pain intensity following miniscrew placement in orthodontic treatment. Timepoint: Immediately after miniscrew placement, 1 hour after miniscrew placement, 12 hours after miniscrew placement, 24 hours after miniscrew placement. Method of measurement: Visual Analog Scale.	—

Secondary

Measure	Time frame
Gingival inflammation around the miniscrew placement site as measured by the modified gingival index, scored as: 0 (no inflammation, pink gingiva, no visible biofilm), 1 (mild inflammation, red gingiva without bleeding), 2 (moderate inflammation, severe red gingiva with mild bleeding on probing), 3 (severe inflammation or miniscrew failure, pronounced bleeding, swelling). Timepoint: 7 days after miniscrew placement. Method of measurement: Modified Gingival Index.;Presence of redness around the miniscrew placement site. Timepoint: 7 days after miniscrew placement. Method of measurement: Clinical examination by an orthodontist.;Presence of blisters around the miniscrew placement site. Timepoint: 7 days after miniscrew placement. Method of measurement: Clinical examination by an orthodontist.	—

Measure

Time frame

Gingival inflammation around the miniscrew placement site as measured by the modified gingival index, scored as: 0 (no inflammation, pink gingiva, no visible biofilm), 1 (mild inflammation, red gingiva without bleeding), 2 (moderate inflammation, severe red gingiva with mild bleeding on probing), 3 (severe inflammation or miniscrew failure, pronounced bleeding, swelling). Timepoint: 7 days after miniscrew placement. Method of measurement: Modified Gingival Index.;Presence of redness around the miniscrew placement site. Timepoint: 7 days after miniscrew placement. Method of measurement: Clinical examination by an orthodontist.;Presence of blisters around the miniscrew placement site. Timepoint: 7 days after miniscrew placement. Method of measurement: Clinical examination by an orthodontist.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactPerham Shirvani

Kermanshah University of Medical Sciences

parham.shirvani@kums.ac.ir+98 83 3421 8154

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026