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Effects of transcutaneous auricular vagus nerve stimulation On diabetic neuropathy

Effects of transcutaneous auricular vagus nerve stimulation On lower limb nerve conduction velocity and perfusion, foot neuropathic pain and quality of life in individuals with type 2 diabetes-double blined controlled clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250602066020N1
Enrollment
20
Registered
2025-06-27
Start date
2025-06-22
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic Neuropathic. Diabetes mellitus due to underlying condition with diabetic neuropathic arthropathy

Interventions

Intervention 1: Intervention group: Intervention will be performed via the cochlea of ??both ears for each participant 3 times a week for 4 weeks. Biphasic symmetrical current with a frequency of 2 Hz

Sponsors

University of social welfare and rehabilitation sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Diabetic neuropathy/ 2.40 to 75 years old/ 3.Both sex/ 4.EMG Electrodiagnosis of diabetic neuropathy consist of small fiber neuropathy and axonal diabetic neuropathy /5.Hyposthesia/ 6. Distal foot pain/ 7.Pain score of 3 to 7 NPRS/ 8.Reading and writing ability

Exclusion criteria

Exclusion criteria: 1.Non diabetic neuropathy/ 2. cigarette or alcohol usage/ 3.Peripheral artery disease cause to foot ulcer and amputation/ 4. Alternative medicine/ 5.Pregnancy and breast feeding/ 6.Heart arrhythmia and heart battery/ 7.Spin radiculopathy and lower limb fracture/ 8.Do not like to join study

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Before and After Trial. Method of measurement: Numeric Pain Rating Scale.

Secondary

MeasureTime frame
Sural Nerve NCV. Timepoint: Before and After Trial. Method of measurement: NCV.;Medial Plantar Nerve NCV. Timepoint: Before and After Trial. Method of measurement: NCV.;Ankle Brachial Index. Timepoint: Before and After Trial. Method of measurement: Pressure Gauge.;Quality of Life. Timepoint: Before and After Trial. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Alizadeh Cham Khale

University of social welfare and rehabilitation sciences

Maryam.Alizadeh9655@gmail.com+98 21 5572 7721

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026