Prostate enlargement, TURP.
Conditions
Interventions
Intervention 1: Intervention group: Tranexamic acid, 500 mg (5 ml) in every 3 liters of irrigation fluid during surgery, with a maximum dose of 50 mg/kg. Intervention 2: Control group: 5 ml of distill
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Individuals over 18 years old who are candidates for TURP based on clinical criteria
Exclusion criteria
Exclusion criteria: Patients with history of finasteride usage Patients who are known case of Prostate cancer Patients who had previous prostate surgery Patients with a history of thromboembolic incidents Patients with a history of Seizure Patients with a history of cardiovascular diseases Patients with Renal failure Patients with history of hypersensitivity to tranexamic acid
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of blood loss during surgery. Timepoint: at the end of surgery. Method of measurement: Measurement of hemoglobin in the output irrigation fluid using the HEMOCUE method.;Serum hemoglobin. Timepoint: 4 & 24 hours after surgery. Method of measurement: Blood sample.;Packed cell transfusion rate. Timepoint: during hospitalization. Method of measurement: number. | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgery time. Timepoint: at the end of surgery. Method of measurement: Minutes. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMOHSEN SARKARIAN
Ahvaz University of Medical Sciences
Outcome results
None listed