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Evaluation of the Effect of Chitosan and Propolis on Furcation Involvements

Clinical and Radiographic Evaluation of Chitosan Gel Combined with Propolis in the Management of Grade II Furcation Defects

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250531065999N1
Enrollment
15
Registered
2025-11-21
Start date
2025-10-23
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Grade II furcation involvement. Gingivitis and periodontal diseases

Interventions

Intervention 1: Intervention Group 1:The 10% propolis gel was prepared in the Department of Pharmacology, Babol University of Medical Sciences. To prepare 5 g of the gel, 2 g of carboxymethyl cellulos

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: moderate to severe periodontitis in buccal or lingual aspect of first or second mandibular molar with grade II furcation involvement plaque index lower than 20% horizontal probing depth in involved tooth equal or more than 3mm

Exclusion criteria

Exclusion criteria: systemic disease drugs and conditions affecting periodontal wound healing smoking anatomic complexity tooth mobility more than class II caries or filling in furcation periapical pathologies

Design outcomes

Primary

MeasureTime frame
Vertical probing depth. Timepoint: before surgery, 6 months after surgery. Method of measurement: measuring with periodontal probe.;Vertical clinical attachment level. Timepoint: before surgery, 6 months after surgery. Method of measurement: measuring with periodontal probe.;Horizontal probing depth. Timepoint: before surgery, 6 months after surgery. Method of measurement: measuring with periodontal probe.;Gingival recession. Timepoint: before surgery, 6 months after surgery. Method of measurement: measuring by periodontal probe.;Gingival index. Timepoint: before surgery, 6 months after surgery. Method of measurement: measuring by periodontal probe.;Radiographic defect depth. Timepoint: before surgery, 6 months after surgery. Method of measurement: photoshop software and digital subtraction.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiloufar Jenabian

Babol University of Medical Sciences

njenabian@hotmail.com+98 11 3219 9592

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026